Autor según el artículo: Blade, Cinta; Aragones, Gerard; Arola-Arnal, Anna; Muguerza, Begona; Isabel Bravo, Francisca; Josepa Salvado, M; Arola, Lluis; Suarez, Manuel
Departamento: Bioquímica i Biotecnologia
Autor/es de la URV: Aragonès Bargalló, Gerard / Arola Arnal, Anna / Arola Ferrer, Luis Maria / BLADÉ SEGARRA, MARIA CINTA / Bravo Vázquez, Francisca Isabel / Muguerza Marquínez, Maria Begoña / Salvadó Rovira, Maria Josepa / Suárez Recio, Manuel
Palabras clave: Proanthocyanidins; Prebiotics; Polyphenols; Molecular mechanisms; Microbiota; Metabolic diseases; Humans; Flavonoids; Diet; Colon; Circadian rhythms; Circadian rhythm; molecular mechanisms; microbiota; metabolic diseases; flavonoids; circadian rhythms
Resumen: © 2016 International Union of Biochemistry and Molecular Biology. Proanthocyanidins (PAs) are the most abundant flavonoids in the human diet. Several epidemiological studies connect PA consumption and health benefits and the designation of PAs as healthy compounds started at the early stages of the 20th century. The beneficial health properties of PAs are attributed to their conjugated and colonic metabolites. Therefore, gut microbial compositions can determine the effectiveness of PAs. Reciprocally, dietary polyphenols can act as prebiotics. Recently, it has also been described that PAs modulate the circadian rhythm. Biochemical and epigenetic mechanisms, including the modulation of microRNAs, allow PAs to modulate cell functionality. PA effects in metabolic diseases are also reviewed.
Áreas temáticas: Saúde coletiva; Química; Molecular medicine; Medicine (miscellaneous); Medicina iii; Medicina ii; Medicina i; Farmacia; Enfermagem; Endocrinology & metabolism; Clinical biochemistry; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Biochemistry & molecular biology; Biochemistry
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: manuel.suarez@urv.cat; franciscaisabel.bravo@urv.cat; anna.arola@urv.cat; gerard.aragones@urv.cat; lluis.arola@urv.cat; begona.muguerza@urv.cat
Fecha de alta del registro: 2025-02-08
Versión del articulo depositado: info:eu-repo/semantics/submittedVersion
Enlace a la fuente original: https://iubmb.onlinelibrary.wiley.com/doi/10.1002/biof.1249
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Biofactors. 42 (1): 5-12
Referencia de l'ítem segons les normes APA: Blade, Cinta; Aragones, Gerard; Arola-Arnal, Anna; Muguerza, Begona; Isabel Bravo, Francisca; Josepa Salvado, M; Arola, Lluis; Suarez, Manuel (2016). Proanthocyanidins in health and disease. Biofactors, 42(1), 5-12. DOI: 10.1002/biof.1249
DOI del artículo: 10.1002/biof.1249
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2016
Tipo de publicación: Journal Publications
Repositori URV