Autor según el artículo: Bladé C, Aragonès G, Arola-Arnal A, Muguerza B, Bravo FI, Salvadó MJ, Arola L, Suárez M.

Departamento: Bioquímica i Biotecnologia

Autor/es de la URV: Aragonès Bargalló, Gerard / Arola Arnal, Anna / Arola Ferrer, Luis Maria / BLADÉ SEGARRA, MARIA CINTA / Bravo Vázquez, Francisca Isabel / Muguerza Marquínez, Maria Begoña / Salvadó Rovira, Maria Josepa / Suárez Recio, Manuel

Palabras clave: Polyphenols Molecular mechanisms Microbiota Metabolic diseases Flavonoids Circadian rhythms molecular mechanisms microbiota metabolic diseases flavonoids circadian rhythms

Resumen: © 2016 International Union of Biochemistry and Molecular Biology. Proanthocyanidins (PAs) are the most abundant flavonoids in the human diet. Several epidemiological studies connect PA consumption and health benefits and the designation of PAs as healthy compounds started at the early stages of the 20th century. The beneficial health properties of PAs are attributed to their conjugated and colonic metabolites. Therefore, gut microbial compositions can determine the effectiveness of PAs. Reciprocally, dietary polyphenols can act as prebiotics. Recently, it has also been described that PAs modulate the circadian rhythm. Biochemical and epigenetic mechanisms, including the modulation of microRNAs, allow PAs to modulate cell functionality. PA effects in metabolic diseases are also reviewed.

Áreas temáticas: Saúde coletiva Química Molecular medicine Medicine (miscellaneous) Medicina iii Medicina ii Medicina i Farmacia Enfermagem Endocrinology & metabolism Clinical biochemistry Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biochemistry & molecular biology Biochemistry

Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/

Direcció de correo del autor: gerard.aragones@urv.cat franciscaisabel.bravo@urv.cat begona.muguerza@urv.cat lluis.arola@urv.cat mariajosepa.salvado@urv.cat anna.arola@urv.cat manuel.suarez@urv.cat

Identificador del autor: 0000-0002-6468-3088 0000-0001-7384-8588 0000-0003-2767-1974 0000-0003-3883-3326 0000-0001-6529-1345 0000-0003-0122-8253

Fecha de alta del registro: 2023-02-22

Versión del articulo depositado: info:eu-repo/semantics/submittedVersion

Enlace a la fuente original: https://iubmb.onlinelibrary.wiley.com/doi/10.1002/biof.1249

URL Documento de licencia: http://repositori.urv.cat/ca/proteccio-de-dades/

Referencia al articulo segun fuente origial: Biofactors. 42 (1): 5-12

Referencia de l'ítem segons les normes APA: Bladé C, Aragonès G, Arola-Arnal A, Muguerza B, Bravo FI, Salvadó MJ, Arola L, Suárez M. (2016). Proanthocyanidins in health and disease. Biofactors, 42(1), 5-12. DOI: 10.1002/biof.1249

DOI del artículo: 10.1002/biof.1249

Entidad: Universitat Rovira i Virgili

Año de publicación de la revista: 2016

Tipo de publicación: Journal Publications