Autor según el artículo: San Miguel I, Arenas M, Carmona R, Rutllan J, Medina-Rivero F, Lara P.
Departamento: Ciències Mèdiques Bàsiques
Autor/es de la URV: Arenas Prat, Meritxell
Palabras clave: Toxicity Radiotherapy Graves’ opthalmopathy radiotherapy graves’ opthalmopathy
Resumen: Graves ophthalmopathy (GO) is an autoimmune disorder and the most frequent extrathyroidal manifestation of Graves' disease. GO is an inflammatory process leading to an increased volume of the extraocular muscles and orbital connective and adipose tissues associated with multiple histopathological changes. Despite recent progress in the understanding of its pathogenesis, GO often remains a major diagnostic and therapeutic challenge. It has become increasingly important to classify patients into categories based on disease severity and activity. Low doses of radiotherapy (RT) have demonstrated a benefit in the treatment of moderate-to-severe GO with very few side effects. New RT techniques deliver a more conformal dose distribution to the target and decrease the dose to normal healthy tissue minimizing the risk of side effects. In this review we briefly analyzed the pathogenesis of GO and discussed the most relevant therapeutic approaches, with particular emphasis in the new RT technics. Appropriately designed and powered clinical studies are necessary to determine the most effective treatment with the lowest risk of side effects.
Áreas temáticas: Ophthalmology Medicina iii Medicina i
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 13194534
Direcció de correo del autor: meritxell.arenas@urv.cat
Identificador del autor: 0000-0003-0815-2570
Fecha de alta del registro: 2023-04-01
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.sciencedirect.com/science/article/pii/S1319453417301133
Referencia al articulo segun fuente origial: Saudi Journal Of Ophthalmology. 32 (2): 139-145
Referencia de l'ítem segons les normes APA: San Miguel I, Arenas M, Carmona R, Rutllan J, Medina-Rivero F, Lara P. (2018). Review of the treatment of Graves' ophthalmopathy: The role of the new radiation techniques. Saudi Journal Of Ophthalmology, 32(2), 139-145. DOI: 10.1016/j.sjopt.2017.09.003
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.1016/j.sjopt.2017.09.003
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2018
Tipo de publicación: Journal Publications