Articles producció científica> Ciències Mèdiques Bàsiques

Low-dose radiation therapy for COVID-19 pneumopathy: what is the evidence?

  • Datos identificativos

    Identificador: imarina:6310799
    Autores:
    Roedel, FranzArenas, MeritxellOtt, Oliver J.Fournier, ClaudiaGeorgakilas, Alexandros G.Tapio, SoileTrott, Klaus-RuedigerGaipl, Udo S.
    Resumen:
    In the current dismal situation of the COVID-19 pandemic, effective management of patients with pneumonia and acute respiratory distress syndrome is of vital importance. Due to the current lack of effective pharmacological concepts, this situation has caused interest in (re)considering historical reports on the treatment of patients with low-dose radiation therapy for pneumonia. Although these historical reports are of low-level evidence per se, hampering recommendations for decision-making in the clinical setting, they indicate effectiveness in the dose range between 0.3 and 1 & x202f;Gy, similar to more recent dose concepts in the treatment of acute and chronic inflammatory/degenerative benign diseases with, e.g., a single dose per fraction of 0.5 & x202f;Gy. This concise review aims to critically review the evidence for low-dose radiation treatment of COVID-19 pneumopathy and discuss whether it is worth investigating in the present clinical situation.
  • Otros:

    Autor según el artículo: Roedel, Franz; Arenas, Meritxell; Ott, Oliver J.; Fournier, Claudia; Georgakilas, Alexandros G.; Tapio, Soile; Trott, Klaus-Ruediger; Gaipl, Udo S.;
    Departamento: Ciències Mèdiques Bàsiques
    Autor/es de la URV: Arenas Prat, Meritxell
    Palabras clave: anti-inflammatory covid-19 low-dose radiation therapy pneumonia Anti-inflammatory Covid-19 Induction Low-dose radiation therapy Pneumonia Radiotherapy Repair Sars-cov-2
    Resumen: In the current dismal situation of the COVID-19 pandemic, effective management of patients with pneumonia and acute respiratory distress syndrome is of vital importance. Due to the current lack of effective pharmacological concepts, this situation has caused interest in (re)considering historical reports on the treatment of patients with low-dose radiation therapy for pneumonia. Although these historical reports are of low-level evidence per se, hampering recommendations for decision-making in the clinical setting, they indicate effectiveness in the dose range between 0.3 and 1 & x202f;Gy, similar to more recent dose concepts in the treatment of acute and chronic inflammatory/degenerative benign diseases with, e.g., a single dose per fraction of 0.5 & x202f;Gy. This concise review aims to critically review the evidence for low-dose radiation treatment of COVID-19 pneumopathy and discuss whether it is worth investigating in the present clinical situation.
    Áreas temáticas: General medicine Oncology Radiology, nuclear medicine & medical imaging Radiology, nuclear medicine and imaging
    Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
    Direcció de correo del autor: meritxell.arenas@urv.cat
    ISSN: 1439099X
    Identificador del autor: 0000-0003-0815-2570
    Fecha de alta del registro: 2023-02-19
    Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
    Enlace a la fuente original: https://link.springer.com/article/10.1007/s00066-020-01635-7
    Referencia al articulo segun fuente origial: Strahlentherapie Und Onkologie. 196 (8): 679-682
    Referencia de l'ítem segons les normes APA: Roedel, Franz; Arenas, Meritxell; Ott, Oliver J.; Fournier, Claudia; Georgakilas, Alexandros G.; Tapio, Soile; Trott, Klaus-Ruediger; Gaipl, Udo S.; (2020). Low-dose radiation therapy for COVID-19 pneumopathy: what is the evidence?. Strahlentherapie Und Onkologie, 196(8), 679-682. DOI: 10.1007/s00066-020-01635-7
    URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
    DOI del artículo: 10.1007/s00066-020-01635-7
    Entidad: Universitat Rovira i Virgili
    Año de publicación de la revista: 2020
    Tipo de publicación: Journal Publications
  • Palabras clave:

    Oncology,Radiology, Nuclear Medicine & Medical Imaging,Radiology, Nuclear Medicine and Imaging
    anti-inflammatory
    covid-19
    low-dose radiation therapy
    pneumonia
    Anti-inflammatory
    Covid-19
    Induction
    Low-dose radiation therapy
    Pneumonia
    Radiotherapy
    Repair
    Sars-cov-2
    General medicine
    Oncology
    Radiology, nuclear medicine & medical imaging
    Radiology, nuclear medicine and imaging
    1439099X
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