Autor según el artículo: Zeng, Liming; Pons-Mercade, Pere; Richard, Tristan; Krisa, Stephanie; Teissedre, Pierre-Louis; Jourdes, Michael;
Departamento: Bioquímica i Biotecnologia
e-ISSN: 1420-3049
Autor/es de la URV: Pons Mercade, Pere
Palabras clave: Resveratrol; Red wine; Procyanidin; Polyphenols; Plant proanthocyanidins; Health; Grape; Elucidation; Crown procyanidin; Condensed tannin; Biosynthesis
Resumen: The structure of a new procyanidin tetramer, which we call a crown procyanidin tetramer, with an unprecedented macrocyclic structure has been characterized for the first time. Its comprehensive spectroscopic analysis revealed that it is a symmetric procyanidin tetramer composed of four (-)-epicatechin sub-units linked alternatively via 48 or 46 B-type interflavanyl linkages to form the macrocyclic structure. This NMR-characterized carbon skeleton has never been reported before for procyanidins in grape or in wine, neither in the plant kingdom. Surprisingly, the crown procyanidin tetramer appeared to be specifically localized in grape skin, contrasting with the oligomeric and polymeric procyanidins present in seed, skin, and bunch stem. Moreover, this crown procyanidin tetramer showed promising protective effects against amyloid- induced toxicity.
Áreas temáticas: Zootecnia / recursos pesqueiros; Saúde coletiva; Química; Psicología; Planejamento urbano e regional / demografia; Physical and theoretical chemistry; Pharmaceutical science; Organic chemistry; Odontología; Nutrição; Molecular medicine; Medicine (miscellaneous); Medicina veterinaria; Medicina iii; Medicina ii; Medicina i; Materiais; Matemática / probabilidade e estatística; Interdisciplinar; Geografía; General medicine; Farmacia; Ensino; Engenharias iv; Engenharias iii; Engenharias ii; Engenharias i; Educação física; Economia; Drug discovery; Ciências biológicas iii; Ciências biológicas ii; Ciências biológicas i; Ciências ambientais; Ciências agrárias i; Ciência de alimentos; Ciência da computação; Chemistry, organic; Chemistry, multidisciplinary; Chemistry (miscellaneous); Biotecnología; Biodiversidade; Biochemistry & molecular biology; Astronomia / física; Analytical chemistry
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: pere.pons@estudiants.urv.cat
Fecha de alta del registro: 2021-10-10
Volumen de revista: 24
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/1420-3049/24/10/1915
Referencia al articulo segun fuente origial: Molecules. 24 (10):
Referencia de l'ítem segons les normes APA: Zeng, Liming; Pons-Mercade, Pere; Richard, Tristan; Krisa, Stephanie; Teissedre, Pierre-Louis; Jourdes, Michael; (2019). Crown Procyanidin Tetramer: A Procyanidin with an Unusual Cyclic Skeleton with a Potent Protective Effect against Amyloid--Induced Toxicity. Molecules, 24(10), -. DOI: 10.3390/molecules24101915
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI del artículo: 10.3390/molecules24101915
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2019
Tipo de publicación: Journal Publications
Repositori URV