Autor según el artículo: Valera-Garrido F; Margalef R; Bosque M; Minaya-Muñoz F; Santafé MM
Departamento: Ciències Mèdiques Bàsiques
Autor/es de la URV: Bosque Alberich, Marc / Santafé Martínez, Manuel
Palabras clave: Skeletal-muscle Percutaneous needle electrolysis Muscles injured by bupivacaine Electromyography recording Bupivacaine Axonal retractions stimulation repair rehabilitation percutaneous needle electrolysis muscles injured by bupivacaine electrotaxis electromyography recording cell bupivacaine
Resumen: Muscle regeneration after a traumatic injury can take an excessively long period of time. The purpose of this study is to assess whether the action of percutaneous needle electrolysis (PNE) accelerates muscle regeneration in cases of partial muscle injuries. The gastrocnemius muscle from adult Swiss male mice was inoculated with bupivacaine. The PNE protocol was applied 48 h after treatment with bupivacaine. Immunofluorescence techniques were performed 72 h after treatment with bupivacaine to evaluate the synaptic contacts. The end plate noise was recorded by electromyography after treatment with bupivacaine. Bupivacaine induced a local injury in muscles, axons were retracted, and the endplate noise decreased at 72 h, while the endplate noise increased in the injured limb where PNE had been applied. Seven days later, the functional values were the same as the controls and they were maintained for 10 days. The endplate noise was significantly greater on the limb treated with the electric current when compared to the limb receiving only bupivacaine, indicating that the use of galvanic current facilitated muscle regeneration at least from a functional point of view. The application of PNE during muscle regeneration in an animal model reduces the recovery time of the damaged muscle tissue.
Áreas temáticas: Química Process chemistry and technology Physics, applied Materials science, multidisciplinary Materials science (miscellaneous) Materials science (all) Materiais Instrumentation General materials science General engineering Fluid flow and transfer processes Engineering, multidisciplinary Engineering (miscellaneous) Engineering (all) Engenharias ii Engenharias i Computer science applications Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, multidisciplinary Biodiversidade Astronomia / física
Acceso a la licencia de uso: https://creativecommons.org/licenses/by/3.0/es/
Direcció de correo del autor: manuel.santafe@urv.cat
Identificador del autor: 0000-0002-5462-5108
Fecha de alta del registro: 2024-09-07
Versión del articulo depositado: info:eu-repo/semantics/publishedVersion
Enlace a la fuente original: https://www.mdpi.com/2076-3417/12/19/10014
URL Documento de licencia: https://repositori.urv.cat/ca/proteccio-de-dades/
Referencia al articulo segun fuente origial: Applied Sciences-Basel. 12 (19):
Referencia de l'ítem segons les normes APA: Valera-Garrido F; Margalef R; Bosque M; Minaya-Muñoz F; Santafé MM (2022). Percutaneous Needle Electrolysis Accelerates Functional Muscle Regeneration in Mice. Applied Sciences-Basel, 12(19), -. DOI: 10.3390/app121910014
DOI del artículo: 10.3390/app121910014
Entidad: Universitat Rovira i Virgili
Año de publicación de la revista: 2022
Tipo de publicación: Journal Publications