Long-term antihypertensive effects and underlying mechanisms of a mixture of protein hydrolysates from a plant-origin coproduct in rats with diet-induced metabolic syndrome

Entity: Universitat Rovira i Virgili (URV)

Confidenciality: Si

Education area(s): Nutrició i Metabolisme

APS: No

Title in different languages: Efectes antihipertensius a llarg termini i mecanismes subjacents d'un mix d'hidrolitzats proteics d'un coproducte d'origen vegetal en rates amb síndrome metabòlica induïda per la dieta

Abstract: Agri-food co-products have emerged as a source of bioactive compounds capable of treating hypertension, such as peptide hydrolysates. Therefore, the aim of this study was to obtain a protein hydrolysate with angiotensin-converting enzyme inhibitory (ACEi) activity, which is an enzyme involved in the development of hypertension. Sixty hydrolysates obtained from an agricultural co-product were tested for ACEi activity, selecting hydrolysates H10 and H60 to test their antihypertensive effect in spontaneously hypertensive rats. According to this study, the H60 hydrolysate was found to have antihypertensive activity, making it a promising compound for use as an antihypertensive agent

Subject: Antihipertensius

Academic year: 2023-2024

Language: en

Work's public defense date: 2023-06-20

Subject areas: Health sciences

Student: Serrano López, Alejandro

Department: Bioquímica i Biotecnologia

Creation date in repository: 2025-05-16

TFM credits: 18

Keywords: agri-food coproducts, antihypertension, bioactive peptides

Title in original language: Long-term antihypertensive effects and underlying mechanisms of a mixture of protein hydrolysates from a plant-origin coproduct in rats with diet-induced metabolic syndrome

Access Rights: info:eu-repo/semantics/restrictedAccess

Project director: Bravo Vázquez, Francisca Isabel