Enteroendocrinal bioactivity of a protein extract

Entity: Universitat Rovira i Virgili (URV)

Confidenciality: No

Education area(s): Nutrició i Metabolisme

APS: No

Title in different languages: Bioactivitat enteroendocrina d'un extracte proteic

Abstract: This study evaluated the enteroendocrine bioactivity of a protein extract using ex vivo and in vivo models. The extract modulated the secretion of intestinal hormones such as ghrelin, GLP-1, PYY, and GIP, particularly in the colon and jejunum. In cafeteria diet-induced obese rats, the 1X treatment slightly reduced weight gain and food intake, while 20X had no effect. Although the extract stimulated anorexigenic hormones, its in vivo impact was mild and not dose-dependent, suggesting other mechanisms may be involved. Further research is needed to explore protein-derived bioactive compounds as potential metabolic modulators.

Subject: Proteïnes

Academic year: 2024-2025

Language: en

Work's public defense date: 2025-06-19

Subject areas: Biochemistry and biotechnology

Student: Angurell Ginés, Pau

Department: Bioquímica i Biotecnologia

Creation date in repository: 2025-12-04

Keywords: protein extract, enterohormones, satiety

Title in original language: Enteroendocrinal bioactivity of a protein extract

Access Rights: info:eu-repo/semantics/openAccess

Project director: Miguéns Gómez, Alba