Identifier: TFM:2478
Authors: Anguera Sánchez, Aina
Abstract:
Pancreatic cancer is a neoplasm associated with a poor prognosis and a high prevalence of malnutrition (MN), a factor that can negatively influence postoperative outcomes. In response to this, prehabilitation programs—integrating preoperative nutritional assessment and intervention—have begun to be implemented, particularly for patients eligible for surgery, which often represents the only curative treatment option for pancreatic neoplasms. The primary objective of this study was to evaluate the preoperative nutritional status of patients undergoing pancreatic surgery and its relationship with subsequent clinical and surgical outcomes. This study was a retrospective observational analysis involving a sample of 34 patients who underwent pancreatic surgery in 2023 at Joan XIII University Hospital. Sociodemographic, clinical, nutritional, surgical, and biochemical variables were collected. Patients were divided into two groups based on the presence or absence of preoperative MN, determined using the Global Leadership Initiative on Malnutrition (GLIM) criteria. Patients with preoperative MN exhibited significantly lower levels of albumin, prealbumin, and transferrin, as well as a greater need for oral nutritional supplements prior to surgery. A significant association was observed between tumor location in the head of the pancreas and the presence of MN. Although no statistically significant differences were found regarding length of hospital stay, complications, or the use of parenteral nutrition, clinically relevant trends were detected. Referral to the nutrition unit was not systematic in all cases. Therefore, these results reinforce the importance of early and systematic nutritional assessment, as well as referral to the nutrition team within prehabilitation protocols. Prospective studies and standardized follow-ups are needed to consolidate this evidence and improve clinical outcomes.
Repositori URV